Friday, October 17, 2025
| Time | Event | Venue/Details |
|---|---|---|
| 8:00pm | Football - Canon-McMillan @ Norwin # | |
| 8:00pm | Football - Central Catholic @ Seneca Valley # | |
| 8:00pm | Football - Hempfield @ Mt. Lebanon # | |
| 8:00pm | Football - North Allegheny @ Pine-Richland | |
| 8:00pm | Football - Fox Chapel vs Shaler # | |
| 8:00pm | Football - North Hills @ Penn Hills # | |
| 8:00pm | Football - Plum vs Kiski Area | |
| 8:00pm | Football - Armstrong @ Penn-Trafford # | |
| 8:00pm | Football - Franklin Regional @ Woodland Hills # | |
| 8:00pm | Football - Gateway @ Latrobe # | |
| 8:00pm | Football - Baldwin vs Peters Township # | |
| 8:00pm | Football - Bethel Park @ South Fayette # | |
| 8:00pm | Football - Moon vs Upper St. Clair # |
# denotes a conference game